Compare 7,638 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Traditional buildings line the serene riverside, surrounded by a well-maintained area with a stone wall and clean pathways.

"Have stayed several times & always great !"

$152 nightly

Aug 27 - Aug 28

Total includes taxes and fees

Two single beds with white linens and colorful bedspreads, a desk with a computer and lamp, and a chair for work and relaxation.

"The hotel and it's location was excellent and convenient to gas stations and numerous dining options. "

$85 nightly

Aug 13 - Aug 14

Total includes taxes and fees

Enjoy unobstructed city views from the pool area, surrounded by glass panels and adjacent to contemporary buildings with large windows.

"Nice place to stay "

$122 nightly

Sep 2 - Sep 3

Total includes taxes and fees

Relax on the outdoor deck with comfortable seating and enjoy the serene views of the lush surroundings.

"Great place to stay and nicely located "

$80 nightly

Aug 13 - Aug 14

Total includes taxes and fees

Two single beds with white bedding and a wooden headboard, a nightstand with a lamp, and a wall-mounted shelf.

"It’s a great place to stay if you need something for a night or two."

$61 nightly

Aug 10 - Aug 11

Total includes taxes and fees

Relax in a spacious room with a large bathtub, adjacent to a comfortable bed with a stylish bedspread, and enjoy a view of lush greenery outside.

"Its was the nicest cheep hotel around."

$69 nightly

Aug 12 - Aug 13

Total includes taxes and fees

Relax in a spacious room with a large bed, mirror, and window with curtains.

"Big bang for your buck. Very convenient to Uber to downtown Frederick. Clean, safe, and quiet - fine for a few nights on a tight budget"

$54 nightly

Aug 24 - Aug 25

Total includes taxes and fees

Relax in a serene outdoor space with comfortable sofas, a chair, and lush greenery.

"Great place to stay "

$93 nightly

Aug 14 - Aug 15

Total includes taxes and fees

Relax in a stylish space with a mix of seating areas and a large round table for gatherings.

"Great service, friendly staff, would definitely stay here again!"

$101 nightly

Aug 13 - Aug 14

Total includes taxes and fees

Relax in a stylish room with a large bed, red accent chair, and city view.

"Very nice place to stay. "

$99 nightly

Aug 10 - Aug 11

Total includes taxes and fees

Experience the sleek, contemporary design of Hyatt Place, set amidst a vibrant urban landscape.

"Great location, friendly staff and very comfortable room"

$95 nightly

Aug 23 - Aug 24

Total includes taxes and fees

Welcome to Best Western, where a beautifully landscaped entrance sets the tone for a relaxing stay.

"Great property, exceptional for the value. "

$77 nightly

Aug 13 - Aug 14

Total includes taxes and fees

Enjoy dining and socializing on the outdoor terrace with city views.

"Went there with my family and we had a great time. "

$135 nightly

Aug 24 - Aug 25

Total includes taxes and fees

Stunning Rocky Gap Casino & Resort entrance, flanked by beautifully maintained gardens.

"Always a pleasure to stay there "

$152 nightly

Sep 1 - Sep 2

Total includes taxes and fees

Step into the State Plaza Hotel, where a sleek entrance welcomes you with a clear view of the lobby area.

"Great place to stay and close to the historical sites. "

$99 nightly

Aug 24 - Aug 25

Total includes taxes and fees

Relax by the pool surrounded by lounge chairs and umbrellas in a sleek, contemporary setting.

"Wonderful stay "

$99 nightly

Aug 10 - Aug 11

Total includes taxes and fees

Welcome to the Ivy City Hotel, featuring a modern architectural design with a striking facade.

"Nice hotel"

$89 nightly

Aug 7 - Aug 8

Total includes taxes and fees

Experience the grandeur of this historic hotel, featuring a central rotunda and multiple wings, surrounded by a beautifully maintained garden.

"Great location and beautiful hotel."

$362 nightly

Aug 7 - Aug 8

Total includes taxes and fees

Enjoy dining in this warm and inviting space with wooden tables, benches, and cushioned chairs.

"Had a great stay! Very nice staff and good area."

$137 nightly

Aug 28 - Aug 29

Total includes taxes and fees

Enjoy a city view from the large window, with a comfortable bed, two bedside tables, and a desk for working or relaxing.

"Nice place to stay"

$119 nightly

Aug 22 - Aug 23

Total includes taxes and fees

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Learn more about Chesapeake & Ohio Canal Towpath

Venture to sights like Chesapeake and Ohio Canal and Fort Frederick State Park as you discover Chesapeake & Ohio Canal Towpath.

See all hotels in Chesapeake & Ohio Canal Towpath

C & O Canal in Williamsport, MD. 185 miles in total dug by hand in the 17th century connecting Washington DC to Cumberland, MD. It was used for the transportation of material and products. It was replaced, almost before it was completed, by the railroads.

Top Chesapeake & Ohio Canal Towpath Hotel Reviews

AC Hotel by Marriott Arlington National Landing

10/10 Excellent

"Excellent hotel, incredible staff, very kind and helpful. Great location, with many restaurants, cafes, and a subway station less than two blocks away. Perfect value for money."

Sheraton Pentagon City Hotel

10/10 Excellent

"This is a centrally located hotel very close to all of the highlighted monuments that most people want to visit. It has very easy access to the highway and it is also within a 10 minute drive to the airport. It is definitely a thumbs up hotel with great service and I will stay here again when visiting DC."